منابع مشابه
Rhinovirus Induces ENA-78 in Airway Epithelium
Epithelial-neutrophil activating peptide-78 (ENA-78) induces neutrophil migration, an early response to viral infection. Rhinovirus serotype 16 (RV16) was used to infect primary bronchial epithelial cells and a cell line (BEAS-2B). Release of ENA-78 protein was measured by enzyme-linked immunosorbent assay, ENA-78 mRNA production was quantified by reverse-transcription polymerase chain reaction...
متن کاملInnate Immunity of Airway Epithelium and COPD
The mammalian immune system consists of two branchesinnate and adaptive immune systems and together they provide protection against infection. Innate immunity is a first line of host defense and is responsible for immediate recognition of pathogens to prevent microbial invasion. In addition innate immune responses also stimulate adaptive immune system (Medzhitov and Janeway, 1997). Cellular com...
متن کاملResistance of differentiated human airway epithelium to infection by rhinovirus.
Virtually all in vitro studies of the effects of rhinovirus on human airway epithelium have used cells grown under conditions known to produce low levels of differentiation. The relevance of the results to native epithelium is questionable. Here we grew primary cultures of human tracheal or nasal epithelium under three conditions. One condition produced pseudostratified, mucociliary cells virtu...
متن کامل[Rhinovirus and airway allergy].
Rhinoviruses cause the majority of common colds, which often provoke wheezing in patients with asthma. The precise mechanisms responsible for the rhinovirus infection-induced exacerbations of bronchial asthma remain uncertain. However, several reports have demonstrated airway hyperresponsiveness, increases in chemical mediators in airway secretions, such as kinin and histamine, and airway infla...
متن کاملThe Relationship between the Severity of Airway Obstruction and COPD Diagnostic Questionnaire Score in COPD Patients
Background & objectives: Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airflow limitation and systemic inflammation which is also associated with pulmonary and extra-pulmonary complications. COPD Diagnostic Questionnaire (CDQ) is a valid questionnaire that is used to identify patients with COPD. The purpose of this study was to determine the relationship between ...
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ژورنال
عنوان ژورنال: Pulmonary and Critical Care Medicine
سال: 2017
ISSN: 2398-3108
DOI: 10.15761/pccm.1000139